منابع مشابه
Myocardial Stunning in Dogs
This study was undertaken to elucidate whether cal-adrenoceptor activity is beneficial to contractile dysfunction during reperfusion after a brief period of ischemia (stunned myocardium) in 54 open-chest dogs. Contractile dysfunction assessed by fractional shortening (FS) was observed 3 hours after the onset of reperfusion following 15 minutes of complete occlusion of the left anterior descendi...
متن کاملMechanism of myocardial "stunning".
Among the numerous mechanisms proposed for myocardial stunning, three appear to be more plausible: 1) generation of oxygen radicals, 2) calcium overload, and 3) excitation-contraction uncoupling. First, the evidence for a pathogenetic role of oxygen-derived free radicals in myocardial stunning is overwhelming. In the setting of a single 15-minute coronary occlusion, mitigation of stunning by an...
متن کاملLate Preconditioning against Myocardial Stunning
Introduction Conscious pigs underwent a sequence of 10 2-min coronary occlusions, each separated by 2 min of reperfusion, for three consecutive days (days 1, 2, and 3 of stage I). The recovery of systolic wall thickening (WTh) after the 10th reperfusion was markedly improved on days 2 and 3 compared with day 1, indicating that the myocardium had become preconditioned against "stunning." 10 d af...
متن کاملMyocardial stunning following respiratory arrest.
Myocardial stunning is defined as a prolonged myocardial dysfunction with gradual return of contractile activity after a brief episode of severe ischemia. Usually it is seen in patients with myocardial infarction following treatment with thrombolytic agents, in patients with angina, and in patients recovering from cardiopulmonary bypass surgery. We report an interesting case of myocardial stunn...
متن کامل‘ ‘ Myocardial stunning ’ ’ remaining questions 1
Dirk J. Duncker , Rainer Schulz , Roberto Ferrari , David Garcia-Dorado , Carlo Guarnieri , Gerd Heusch , Pieter D. Verdouw a,) a Experimental Cardiology, Thoraxcenter, Erasmus UniÕersity Rotterdam, P.O. Box 1738, 3000 DR Rotterdam, Netherlands b Department of Pathophysiology, UniÕersity of Essen, Essen, Germany c Fondazione Clinica del LaÕoro, Brescia, Italy d Hospital General UniÕersitairi, V...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 1998
ISSN: 1755-3245,0008-6363
DOI: 10.1016/s0008-6363(98)00061-3